Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3046
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk3
Name: mitogen activated protein kinase 3
Acc ID: CHEBI:17833
Term: gentamycin
Definition: Any of a group of aminoglycoside antibiotics produced by fermentation of some Micromonospora spp.
Chemical ID: MESH:D005839
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk3increases phosphorylationEXP 6480464CTDGentamicins results in increased phosphorylation of MAPK3 proteinPMID:34350654
Mapk3multiple interactionsEXP 6480464CTD[Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of MAPK3 proteinPMID:30545405
Mapk3multiple interactionsISOMAPK3 (Homo sapiens)6480464CTD2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Gentamicins results in increased phosphorylation of and results in increased activity of MAPK3 protein]; CASR protein promotes the reaction [Gentamicins results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Gentamicins results in increased phosphorylation of and results in increased activity of MAPK3 proteinPMID:17537980
Go Back to source page   Continue to Ontology report