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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2944
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Junb
Name: JunB proto-oncogene, AP-1 transcription factor subunit
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Junbincreases expressionEXP 6480464CTDEstradiol results in increased expression of JUNB mRNAPMID:32145629
Junbaffects expressionISOJunb (Mus musculus)6480464CTDEstradiol affects the expression of JUNB mRNAPMID:15598610
Junbdecreases expressionISOJUNB (Homo sapiens)6480464CTDEstradiol results in decreased expression of JUNB mRNAPMID:23019147 PMID:24758408 PMID:25321415
Junbincreases expressionISOJUNB (Homo sapiens)6480464CTDEstradiol results in increased expression of JUNB mRNAPMID:16029874 PMID:31646340
Junbincreases expressionISOJunb (Mus musculus)6480464CTDEstradiol results in increased expression of JUNB mRNAPMID:25210133
Junbmultiple interactionsISOJUNB (Homo sapiens)6480464CTD[Estradiol co-treated with EGF protein] results in increased expression of JUNB mRNA; [Estradiol co-treated with TGFB1 protein] results in increased expression of JUNB mRNAPMID:24758408 PMID:30165855
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