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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2926
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Itgam
Name: integrin subunit alpha M
Acc ID: CHEBI:28262
Term: dimethyl sulfoxide
Definition: A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
Chemical ID: MESH:D004121
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Itgamincreases expressionISOITGAM (Homo sapiens)6480464CTDDimethyl Sulfoxide results in increased expression of ITGAM proteinPMID:16617325 PMID:22118543 PMID:7909661
Itgammultiple interactionsISOITGAM (Homo sapiens)6480464CTD[Tretinoin co-treated with Dimethyl Sulfoxide] results in increased expression of ITGAM protein; Dexamethasone inhibits the reaction [Dimethyl Sulfoxide results in increased expression of ITGAM protein]; Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of ITGAM protein]PMID:15964820 PMID:26330309 PMID:7909661
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