GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Insr | decreases expression | EXP | | 6480464 | CTD | Fructose results in decreased expression of INSR mRNA; Fructose results in decreased expression of INSR protein | PMID:14573337 | Insr | decreases phosphorylation | EXP | | 6480464 | CTD | Fructose results in decreased phosphorylation of INSR protein | PMID:22426011 PMID:24491314 | Insr | multiple interactions | EXP | | 6480464 | CTD | [Fructose co-treated with Oleanolic Acid] results in increased expression of INSR mRNA; [Fructose co-treated with Sodium Chloride, Dietary deficiency] results in decreased expression of INSR mRNA; [Fructose co-treated with Sodium Chloride, Dietary deficiency] results in decreased expression of INSR protein; Allopurinol inhibits the reaction [Fructose results in decreased phosphorylation of INSR protein]; Quercetin inhibits the reaction [Fructose results in decreased phosphorylation of INSR protein]; Rutin inhibits the reaction [Fructose results in decreased phosphorylation of INSR protein] | PMID:14633139 PMID:22426011 PMID:24491314 PMID:24704288 | |
Go Back to source page | Continue to Ontology report |