GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Insr | increases phosphorylation | EXP | | 6480464 | CTD | resveratrol results in increased phosphorylation of INSR protein | PMID:18426865 | Insr | multiple interactions | EXP | | 6480464 | CTD | ESR1 protein promotes the reaction [resveratrol results in increased phosphorylation of INSR protein]; fulvestrant inhibits the reaction [resveratrol results in increased phosphorylation of INSR protein]; resveratrol inhibits the reaction [Oxygen deficiency results in increased expression of INSR protein] | PMID:18426865 PMID:25352008 | Insr | multiple interactions | ISO | Insr (Mus musculus) | 6480464 | CTD | resveratrol binds to and results in decreased phosphorylation of and results in decreased activity of INSR protein | PMID:22935344 | Insr | multiple interactions | ISO | INSR (Homo sapiens) | 6480464 | CTD | resveratrol inhibits the reaction [IRS2 gene mutant form inhibits the reaction [INS protein results in increased phosphorylation of INSR protein]]; resveratrol inhibits the reaction [Pyruvaldehyde results in decreased phosphorylation of INSR protein]; resveratrol inhibits the reaction [Streptozocin inhibits the reaction [INS protein results in increased phosphorylation of INSR protein]] | PMID:22917016 PMID:25808216 | |
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