GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ins2 | multiple interactions | ISO | Ins2 (Mus musculus) | 6480464 | CTD | fulvestrant inhibits the reaction [4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol results in increased expression of INS2 protein]; fulvestrant inhibits the reaction [[[INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone] co-treated with bisphenol A] results in increased activity of ESR2 protein]; fulvestrant inhibits the reaction [bisphenol A results in increased expression of INS2 protein]; fulvestrant inhibits the reaction [Estradiol results in increased expression of INS2 protein] | PMID:18446233 PMID:26944108 | Ins2 | multiple interactions | ISO | INS (Homo sapiens) | 6480464 | CTD | [bisphenol A co-treated with Fulvestrant] results in increased methylation of INS gene; Fulvestrant inhibits the reaction [bisphenol A inhibits the reaction [INS protein results in increased uptake of Glucose]]; Fulvestrant inhibits the reaction [tributyltin promotes the reaction [Glucose results in increased secretion of INS protein]]; PPARG protein affects the reaction [Fulvestrant inhibits the reaction [bisphenol A inhibits the reaction [INS protein results in increased uptake of Glucose]]] | PMID:28180948 PMID:31601247 PMID:32623698 | | ||||||||||||||||||||||
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