GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ins2 | multiple interactions | ISO | Ins2 (Mus musculus) | 6480464 | CTD | [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of stearic acid analog; [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased abundance of stearic acid analog | PMID:26820058 | Ins2 | multiple interactions | ISO | INS (Homo sapiens) | 6480464 | CTD | INS protein inhibits the reaction [stearic acid results in decreased expression of CYP3A4 mRNA]; INS protein inhibits the reaction [stearic acid results in increased chemical synthesis of 6-hydroxychlorzoxazone]; INS protein inhibits the reaction [stearic acid results in increased hydroxylation of Chlorzoxazone] | PMID:26739624 | | ||||||||||||||||||||||
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