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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2916
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ins2
Name: insulin 2
Acc ID: CHEBI:17737
Term: desmosterol
Definition: A cholestanoid that is cholesta-5,24-diene substituted by a beta-hydroxy group at position 3. It is an intermediate metabolite obtained during the synthesis of cholesterol.
Chemical ID: MESH:D003897
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ins2multiple interactionsISOIns2 (Mus musculus)6480464CTD[1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of Desmosterol analog; [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased abundance of Desmosterol analogPMID:26820058
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