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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2900
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il5
Name: interleukin 5
Acc ID: CHEBI:50594
Term: carbon nanotube
Definition: A molecule consisting of a graphene cylinder or two or more concentric graphene cylinders.
Chemical ID: MESH:D037742
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il5affects expressionISOIl5 (Mus musculus)6480464CTDNanotubes, Carbon affects the expression of IL5 mRNAPMID:23845593
Il5decreases secretionISOIl5 (Mus musculus)6480464CTDNanotubes, Carbon results in decreased secretion of IL5 proteinPMID:19371758
Il5increases expressionISOIl5 (Mus musculus)6480464CTDNanotubes, Carbon results in increased expression of IL5 mRNA; Nanotubes, Carbon results in increased expression of IL5 proteinPMID:19428951 PMID:22293422 PMID:25554681
Il5increases expressionISOIL5 (Homo sapiens)6480464CTDNanotubes, Carbon results in increased expression of IL5 mRNAPMID:25511174
Il5multiple interactionsISOIl5 (Mus musculus)6480464CTD[Antigens, Dermatophagoides co-treated with Nanotubes, Carbon] results in increased expression of IL5 mRNA; [Nanotubes, Carbon co-treated with Ovalbumin] results in increased expression of IL5 protein; STAT1 protein affects the reaction [[Nanotubes, Carbon co-treated with Ovalbumin] results in increased expression of IL5 protein]PMID:25807359 PMID:26091108
Il5multiple interactionsISOIL5 (Homo sapiens)6480464CTDNanotubes, Carbon inhibits the reaction [Antigens, Dermatophagoides results in increased secretion of IL5 protein]PMID:23266719
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