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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2900
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il5
Name: interleukin 5
Acc ID: CHEBI:3207
Term: budesonide
Definition: A glucocorticoid steroid having a highly oxygenated pregna-1,4-diene structure. It is used mainly in the treatment of asthma and non-infectious rhinitis and for treatment and prevention of nasal polyposis.
Chemical ID: MESH:D019819
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il5decreases expressionISOIl5 (Mus musculus)6480464CTDBudesonide results in decreased expression of IL5 proteinPMID:12406821 PMID:15086961 PMID:7988651
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