Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2891
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il1b
Name: interleukin 1 beta
Acc ID: CHEBI:75095
Term: chrysin
Definition: A dihydroxyflavone in which the two hydroxy groups are located at positions 5 and 7.
Chemical ID: MESH:C043561
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il1bmultiple interactionsEXP 6480464CTDchrysin inhibits the reaction [Acetaminophen results in increased expression of IL1B protein]; chrysin inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; chrysin inhibits the reaction [Isoniazid results in increased expression of IL1B mRNA]PMID:28682524 PMID:33121995 PMID:37263553
Il1bdecreases expressionISOIL1B (Homo sapiens)6480464CTDchrysin results in decreased expression of IL1B mRNAPMID:20816778
Il1bmultiple interactionsISOIl1b (Mus musculus)6480464CTDchrysin inhibits the reaction [Oxidopamine results in increased expression of IL1B protein]PMID:29054324
Il1bmultiple interactionsISOIL1B (Homo sapiens)6480464CTDchrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1B mRNA]; chrysin inhibits the reaction [IL1B protein results in increased phosphorylation of NFKBIA protein]; chrysin inhibits the reaction [IL1B protein results in increased secretion of CXCL8 protein]; chrysin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; chrysin inhibits the reaction [nickel chloride results in increased expression of IL1B protein]PMID:18377686 PMID:21515303 PMID:30016632 PMID:34774662
Go Back to source page   Continue to Ontology report