Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2891
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il1b
Name: interleukin 1 beta
Acc ID: CHEBI:51913
Term: Goe 6976
Definition: An indolocarbazole that has formula C24H18N4O.
Chemical ID: MESH:C081021
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il1bmultiple interactionsISOIL1B (Homo sapiens)6480464CTDGo 6976 inhibits the reaction [IL1B protein affects the localization of NCF1 protein]; Go 6976 inhibits the reaction [IL1B protein results in increased abundance of Reactive Oxygen Species]; Go 6976 inhibits the reaction [IL1B protein results in increased expression of VCAM1 mRNA]; Go 6976 inhibits the reaction [IL1B protein results in increased expression of VCAM1 protein]; Go 6976 inhibits the reaction [IL1B protein results in increased phosphorylation of SRC protein]PMID:19281832
Go Back to source page   Continue to Ontology report