Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Asbestos, Crocidolite promotes the reaction [IL1B protein results in increased expression of VCAM1 mRNA]; Asbestos, Crocidolite promotes the reaction [IL1B protein results in increased expression of VCAM1 protein]; IL1B protein promotes the reaction [Asbestos, Crocidolite results in increased expression of CCL2 mRNA]; IL1B protein promotes the reaction [Asbestos, Crocidolite results in increased secretion of CCL2 protein]
Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; CYBA protein affects the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; Deferoxamine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; Lignans inhibits the reaction [Asbestos, Crocidolite results in increased expression of IL1B protein]; NLRP3 protein affects the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; PYCARD protein affects the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; TXN protein affects the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]
[Asbestos, Crocidolite co-treated with IL1B protein] results in increased abundance of 3-nitrotyrosine; [Asbestos, Crocidolite co-treated with IL1B protein] results in increased abundance of Nitrates; [Asbestos, Crocidolite co-treated with IL1B protein] results in increased expression of NOS2 mRNA; [Asbestos, Crocidolite co-treated with IL1B protein] results in increased expression of NOS2 protein; acetovanillone inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; Asbestos, Crocidolite promotes the reaction [IL1B protein results in increased abundance of Nitric Oxide]; Asbestos, Crocidolite promotes the reaction [TNF protein results in increased secretion of IL1B protein]; Asbestos, Crocidolite results in increased expression of and results in increased secretion of IL1B protein; CASP1 protein affects the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; Cytochalasin B inhibits the reaction [Asbestos, Crocidolite promotes the reaction [IL1B protein results in increased abundance of Nitric Oxide]]; Cytochalasin D inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; diphenyleneiodonium inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; Interleukin 1 Receptor Antagonist Protein inhibits the reaction [Asbestos, Crocidolite results in increased expression of IL1B mRNA]; Interleukin 1 Receptor Antagonist Protein inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; latrunculin A inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; NLRP3 protein affects the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; NLRP3 protein promotes the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; pimagedine inhibits the reaction [Asbestos, Crocidolite promotes the reaction [IL1B protein results in increased abundance of Nitric Oxide]]; Potassium Chloride inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; PYCARD protein affects the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; ROCK1 protein promotes the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; ROCK2 protein promotes the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; TNF protein promotes the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; tyrosyl-valyl-alanyl-aspartic acid fluoromethyl ketone inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; Y 27632 inhibits the reaction [Asbestos, Crocidolite results in increased expression of and results in increased secretion of IL1B protein]
