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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2891
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il1b
Name: interleukin 1 beta
Acc ID: CHEBI:30778
Term: gallic acid
Definition: A trihydroxybenzoic acid in which the hydroxy groups are at positions 3, 4, and 5.
Chemical ID: MESH:D005707
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il1bmultiple interactionsEXP 6480464CTDGallic Acid analog inhibits the reaction [Indomethacin results in increased expression of IL1B mRNA]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein]; Gallic Acid inhibits the reaction [cobaltous chloride results in increased expression of IL1B protein]; Gallic Acid inhibits the reaction [Glucose results in increased secretion of IL1B protein]; Gallic Acid inhibits the reaction [Quinolinic Acid results in increased expression of IL1B protein]PMID:23892052 PMID:26341651 PMID:29981346 PMID:31362009
Il1bmultiple interactionsISOIl1b (Mus musculus)6480464CTDGallic Acid inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL1B protein]PMID:35196152
Il1bmultiple interactionsISOIL1B (Homo sapiens)6480464CTD[Gallic Acid co-treated with Butyric Acid co-treated with verbascose] affects the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased secretion of IL1B protein]; Gallic Acid inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased secretion of IL1B protein]PMID:33130239
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