GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il1b | increases expression | EXP | | 6480464 | CTD | Formaldehyde results in increased expression of IL1B protein | PMID:20658762 PMID:21983654 | Il1b | multiple interactions | EXP | | 6480464 | CTD | [Capsaicin results in increased susceptibility to Formaldehyde] which results in increased expression of IL1B mRNA; acetovanillone inhibits the reaction [Formaldehyde results in increased expression of IL1B protein]; Indomethacin inhibits the reaction [Formaldehyde results in increased expression of IL1B protein] | PMID:21983654 PMID:28005965 | Il1b | affects expression | ISO | Il1b (Mus musculus) | 6480464 | CTD | Formaldehyde affects the expression of IL1B protein | PMID:29315975 | Il1b | decreases expression | ISO | Il1b (Mus musculus) | 6480464 | CTD | Formaldehyde results in decreased expression of IL1B protein | PMID:15003329 | Il1b | decreases expression | ISO | IL1B (Homo sapiens) | 6480464 | CTD | Formaldehyde results in decreased expression of IL1B mRNA | PMID:29594315 | Il1b | increases expression | ISO | Il1b (Mus musculus) | 6480464 | CTD | Formaldehyde results in increased expression of IL1B protein | PMID:30395894 | Il1b | increases expression | ISO | IL1B (Homo sapiens) | 6480464 | CTD | Formaldehyde results in increased expression of IL1B mRNA | PMID:27664576 | Il1b | multiple interactions | ISO | Il1b (Mus musculus) | 6480464 | CTD | 2-amino-3-(4'-N,N-bis(2-chloroethyl)amino)phenylpropionic acid N-oxide inhibits the reaction [[Formaldehyde co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]; [Ovalbumin co-treated with Formaldehyde] results in increased expression of and results in increased secretion of IL1B protein; [Rutin co-treated with Meloxicam] affects the reaction [Formaldehyde affects the expression of IL1B protein]; epigallocatechin gallate inhibits the reaction [Formaldehyde results in increased expression of IL1B protein]; Formaldehyde promotes the reaction [ovalbumin-alum results in increased secretion of IL1B protein]; Meloxicam affects the reaction [Formaldehyde affects the expression of IL1B protein]; Rutin affects the reaction [Formaldehyde affects the expression of IL1B protein] | PMID:23671638 PMID:29315975 PMID:30395894 PMID:37105513 | Il1b | multiple interactions | ISO | IL1B (Homo sapiens) | 6480464 | CTD | Formaldehyde results in increased expression of and results in increased secretion of IL1B protein | PMID:18082304 | |
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