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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2891
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il1b
Name: interleukin 1 beta
Acc ID: CHEBI:16356
Term: 3',5'-cyclic GMP
Definition: A 3',5'-cyclic purine nucleotide in which the purine nucleobase is specified as guanidine.
Chemical ID: MESH:D006152
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il1bincreases abundanceEXP 6480464CTDIL1B protein results in increased abundance of Cyclic GMPPMID:11506125
Il1bmultiple interactionsEXP 6480464CTDHalothane inhibits the reaction [IL1B protein results in increased abundance of Cyclic GMP]PMID:11506125
Il1bmultiple interactionsISOIL1B (Homo sapiens)6480464CTD[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased abundance of Cyclic GMP; nitroaspirin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased abundance of Cyclic GMP]PMID:14762100
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