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GENE - TERM ANNOTATION REPORT

RGD ID: 2886
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il10
Name: interleukin 10
Acc ID: DOID:9146
Term: visceral leishmaniasis
Definition: A leishmaniasis that is the most severe form of the disease caused by protozoan parasites of the Leishmania genus, resulting in the infection of the internal organs such as liver, spleen and bone marrow. The symptoms include fever, weight loss, and an enlarged spleen and liver. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Visceral_leishmaniasis "DO" "DO", http://www.dpd.cdc.gov/dpdx/HTML/Leishmaniasis.htm "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il10 ISOIL10 (Homo sapiens)14975172RGD  
Il10 ISOIL10 (Homo sapiens)11554173CTDCTD Direct Evidence: marker/mechanismPMID:15716043 PMID:17404324 PMID:22461696
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