GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il10 | multiple interactions | EXP | | 6480464 | CTD | CD40 protein affects the reaction [Curcumin affects the reaction [Lipopolysaccharides affects the expression of IL10 protein]]; Curcumin affects the reaction [Lipopolysaccharides affects the expression of IL10 protein]; Curcumin analog inhibits the reaction [Copper Sulfate results in decreased secretion of IL10 protein]; Curcumin inhibits the reaction [Copper Sulfate results in decreased secretion of IL10 protein]; Curcumin inhibits the reaction [Methotrexate results in decreased secretion of IL10 protein]; Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of IL10 mRNA]; ICAM1 protein affects the reaction [Curcumin affects the reaction [Lipopolysaccharides affects the expression of IL10 protein]] | PMID:15604057 PMID:16867261 PMID:20885979 PMID:30431687 PMID:35549587 | Il10 | decreases expression | ISO | Il10 (Mus musculus) | 6480464 | CTD | Curcumin results in decreased expression of IL10 protein | PMID:21397623 | Il10 | multiple interactions | ISO | IL10 (Homo sapiens) | 6480464 | CTD | Curcumin inhibits the reaction [nickel chloride results in increased expression of IL10 protein]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of IL10 mRNA]; Curcumin promotes the reaction [IFNA1 protein results in increased expression of IL10 protein]; Curcumin promotes the reaction [IFNB1 protein results in increased expression of IL10 protein] | PMID:17979888 PMID:23452621 PMID:30016632 | |
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