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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2886
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il10
Name: interleukin 10
Acc ID: CHEBI:27568
Term: selenium atom
Definition: A chalcogen that has formula Se.
Chemical ID: MESH:D012643
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il10multiple interactionsEXP 6480464CTD[Vanadium co-treated with Selenium co-treated with Vitamin E co-treated with Chromium] inhibits the reaction [Streptozocin results in decreased expression of IL10 protein]; Selenium affects the reaction [Mercuric Chloride results in decreased expression of IL10 protein]PMID:15862027 PMID:26089086
Il10multiple interactionsISOIl10 (Mus musculus)6480464CTD[Drugs, Chinese Herbal co-treated with Selenium] results in increased expression of IL10 mRNAPMID:24626144
Il10multiple interactionsISOIL10 (Homo sapiens)6480464CTD[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in decreased expression of IL10 mRNA; [Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in increased expression of IL10 mRNAPMID:21481475
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