GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il10 | increases expression | ISO | IL10 (Homo sapiens) | 6480464 | CTD | Tretinoin results in increased expression of IL10 mRNA | PMID:15189689 PMID:16322758 PMID:16872382 | Il10 | increases secretion | ISO | IL10 (Homo sapiens) | 6480464 | CTD | Tretinoin results in increased secretion of IL10 protein | PMID:16872382 PMID:17209053 | Il10 | multiple interactions | ISO | IL10 (Homo sapiens) | 6480464 | CTD | 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Tretinoin promotes the reaction [CPG-oligonucleotide results in increased secretion of IL10 protein]]; [Tretinoin results in increased secretion of IL10 protein] promotes the reaction [CPG-oligonucleotide results in increased expression of CCND3 protein]; RARA protein affects the reaction [Tretinoin results in increased secretion of IL10 protein]; Ro 41-5253 inhibits the reaction [Tretinoin results in increased secretion of IL10 protein]; Tretinoin promotes the reaction [CPG-oligonucleotide results in increased secretion of IL10 protein]; Tretinoin promotes the reaction [Lipopolysaccharides results in increased expression of IL10 mRNA]; Tretinoin promotes the reaction [Lipopolysaccharides results in increased expression of IL10 protein] | PMID:16872382 PMID:17209053 PMID:17253143 | | ||||||||||||||||||||||
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