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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2869 Species: Rattus norvegicus RGD Object: Gene Symbol: Igf1r Name: insulin-like growth factor 1 receptor

Acc ID: CHEBI:34687 Term: dibutyl phthalate Definition: The dibutyl ester of benzene-1,2-dicarboxylic acid. CasRN: 84-74-2 Chemical ID: MESH:D003993

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	ISO	RGD:10766	6480464	CTD	Dibutyl Phthalate results in increased expression of IGF1R mRNA	PMID:21266533
increases expression	EXP		6480464	CTD	Dibutyl Phthalate results in increased expression of IGF1R mRNA Dibutyl Phthalate results in increased expression of IGF1R protein	PMID:15829613