GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Igf1 | affects activity | EXP | | 6480464 | CTD | Cyclosporine affects the activity of IGF1 protein | PMID:11548882 | Igf1 | multiple interactions | EXP | | 6480464 | CTD | Cyclosporine inhibits the reaction [IGF1 protein results in increased expression of NPPA mRNA] | PMID:11548882 | Igf1 | affects expression | ISO | IGF1 (Homo sapiens) | 6480464 | CTD | Cyclosporine affects the expression of IGF1 mRNA | PMID:33631201 | Igf1 | decreases expression | ISO | Igf1 (Mus musculus) | 6480464 | CTD | Cyclosporine results in decreased expression of IGF1 mRNA | PMID:19770486 | Igf1 | decreases expression | ISO | IGF1 (Homo sapiens) | 6480464 | CTD | Cyclosporine results in decreased expression of IGF1 mRNA | PMID:20106945 PMID:27989131 | Igf1 | increases secretion | ISO | IGF1 (Homo sapiens) | 6480464 | CTD | Cyclosporine results in increased secretion of IGF1 protein | PMID:16882103 | Igf1 | multiple interactions | ISO | IGF1 (Homo sapiens) | 6480464 | CTD | Cyclosporine inhibits the reaction [IGF1 protein results in increased activity of HIF1A protein]; Cyclosporine inhibits the reaction [IGF1 protein results in increased expression of HIF1A protein] | PMID:16682453 | |
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