GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Htr2c | increases expression | ISO | HTR2C (Homo sapiens) | 6480464 | CTD | Mianserin results in increased expression of HTR2C protein | PMID:18083778 | Htr2c | multiple interactions | ISO | Htr2c (Mus musculus) | 6480464 | CTD | [Mianserin binds to and results in decreased activity of HTR2C protein] which results in decreased susceptibility to Methamphetamine; Mianserin binds to and results in decreased activity of HTR2C protein | PMID:10978843 PMID:15213358 | Htr2c | multiple interactions | ISO | HTR2C (Homo sapiens) | 6480464 | CTD | 6-chloro-5-methyl-1-((2-(2-methylpyrid-3-yloxy)pyrid-5-yl)carbamoyl)indoline inhibits the reaction [Mianserin results in increased expression of HTR2C protein]; Mianserin binds to and affects the activity of HTR2C protein | PMID:18083778 | |
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