GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Hspa5 | affects expression | EXP | | 6480464 | CTD | bisphenol A affects the expression of HSPA5 mRNA | PMID:30903817 | Hspa5 | decreases expression | EXP | | 6480464 | CTD | bisphenol A results in decreased expression of HSPA5 mRNA | PMID:30816183 PMID:32528016 PMID:33296240 PMID:34947998 | Hspa5 | increases expression | EXP | | 6480464 | CTD | bisphenol A results in increased expression of HSPA5 mRNA; bisphenol A results in increased expression of HSPA5 protein | PMID:22649256 PMID:25181051 PMID:35699857 | Hspa5 | increases methylation | EXP | | 6480464 | CTD | bisphenol A results in increased methylation of HSPA5 gene | PMID:28505145 | Hspa5 | multiple interactions | EXP | | 6480464 | CTD | 18alpha-glycyrrhetinic acid inhibits the reaction [bisphenol A results in increased expression of HSPA5 mRNA] | PMID:35699857 | Hspa5 | affects expression | ISO | HSPA5 (Homo sapiens) | 6480464 | CTD | bisphenol A affects the expression of HSPA5 mRNA | PMID:20170705 PMID:30903817 | Hspa5 | decreases expression | ISO | Hspa5 (Mus musculus) | 6480464 | CTD | bisphenol A results in decreased expression of HSPA5 protein | PMID:21705745 PMID:36613676 | Hspa5 | decreases expression | ISO | HSPA5 (Homo sapiens) | 6480464 | CTD | bisphenol A results in decreased expression of HSPA5 protein | PMID:34186270 | Hspa5 | increases expression | ISO | Hspa5 (Mus musculus) | 6480464 | CTD | bisphenol A results in increased expression of HSPA5 mRNA; bisphenol A results in increased expression of HSPA5 protein | PMID:12233820 PMID:12732195 PMID:16713995 PMID:20807545 PMID:28279065 PMID:28641223 PMID:33930482 | Hspa5 | increases expression | ISO | HSPA5 (Homo sapiens) | 6480464 | CTD | bisphenol A results in increased expression of HSPA5 mRNA; bisphenol A results in increased expression of HSPA5 protein | PMID:25333893 PMID:25619500 PMID:37567409 | Hspa5 | multiple interactions | ISO | Hspa5 (Mus musculus) | 6480464 | CTD | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of HSPA5 mRNA; [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of HSPA5 protein; [Palmitates co-treated with bisphenol A] results in increased expression of HSPA5 mRNA; Glucose affects the reaction [bisphenol A results in decreased expression of HSPA5 protein]; Oleic Acid inhibits the reaction [[Palmitates co-treated with bisphenol A] results in increased expression of HSPA5 mRNA] | PMID:21705745 PMID:32976987 PMID:37364641 | Hspa5 | multiple interactions | ISO | HSPA5 (Homo sapiens) | 6480464 | CTD | [bisphenol A co-treated with ESR1 protein] results in increased expression of HSPA5 protein | PMID:19269315 | | ||||||||||||||||||||||
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