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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2843
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hspa5
Name: heat shock protein family A (Hsp70) member 5
Acc ID: CHEBI:3305
Term: Calcimycin
Definition: An aminobenzoic acid that has formula C29H37N3O6.
Chemical ID: MESH:D000001
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hspa5increases expressionISOHspa5 (Mus musculus)6480464CTDCalcimycin results in increased expression of HSPA5 mRNA; Calcimycin results in increased expression of HSPA5 proteinPMID:14610226 PMID:18799549
Hspa5increases expressionISOHSPA5 (Homo sapiens)6480464CTDCalcimycin results in increased expression of HSPA5 mRNA; Calcimycin results in increased expression of HSPA5 proteinPMID:12147617 PMID:19139269 PMID:19428936 PMID:27064126
Hspa5multiple interactionsISOHSPA5 (Homo sapiens)6480464CTDQuercetin inhibits the reaction [Calcimycin results in increased expression of HSPA5 mRNA]; Quercetin inhibits the reaction [Calcimycin results in increased expression of HSPA5 protein]PMID:19428936
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