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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2843
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hspa5
Name: heat shock protein family A (Hsp70) member 5
Acc ID: CHEBI:17833
Term: gentamycin
Definition: Any of a group of aminoglycoside antibiotics produced by fermentation of some Micromonospora spp.
Chemical ID: MESH:D005839
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hspa5increases expressionEXP 6480464CTDGentamicins results in increased expression of HSPA5 mRNA; Gentamicins results in increased expression of HSPA5 proteinPMID:17567590 PMID:18172885 PMID:22061828 PMID:33387578
Hspa5increases expressionISOHspa5 (Mus musculus)6480464CTDGentamicins results in increased expression of HSPA5 mRNA; Gentamicins results in increased expression of HSPA5 proteinPMID:29751043
Hspa5multiple interactionsISOHspa5 (Mus musculus)6480464CTDursodoxicoltaurine inhibits the reaction [Gentamicins results in increased expression of HSPA5 mRNA]; ursodoxicoltaurine inhibits the reaction [Gentamicins results in increased expression of HSPA5 protein]PMID:29751043
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