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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2827
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hras
Name: HRas proto-oncogene, GTPase
Acc ID: CHEBI:82405
Term: Benzoyl peroxide
Definition: A carbonyl compound that has formula C14H10O4.
Chemical ID: MESH:D001585
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hrasincreases mutagenesisISOHras (Mus musculus)6480464CTDBenzoyl Peroxide results in increased mutagenesis of HRAS genePMID:11241758
Hrasmultiple interactionsISOHras (Mus musculus)6480464CTD[9,10-Dimethyl-1,2-benzanthracene co-treated with Benzoyl Peroxide] results in increased expression of HRAS mRNA; [9,10-Dimethyl-1,2-benzanthracene co-treated with Benzoyl Peroxide] results in increased mutagenesis of HRAS genePMID:11241758 PMID:3115617
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