GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Hmox1 | decreases expression | EXP | | 6480464 | CTD | Nitroprusside results in decreased expression of HMOX1 protein | PMID:18311796 PMID:29353218 | Hmox1 | increases expression | EXP | | 6480464 | CTD | Nitroprusside results in increased expression of HMOX1 protein | PMID:16439612 | Hmox1 | multiple interactions | EXP | | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Nitroprusside results in increased expression of HMOX1 protein]; Cilostazol inhibits the reaction [Nitroprusside results in decreased expression of HMOX1 protein]; Deferoxamine inhibits the reaction [Nitroprusside results in increased expression of HMOX1 protein]; KT 5720 inhibits the reaction [Nitroprusside results in increased expression of HMOX1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Nitroprusside results in increased expression of HMOX1 protein]; Nitroprusside inhibits the reaction [sulforaphane results in increased expression of HMOX1 protein]; pyrazolanthrone inhibits the reaction [Nitroprusside results in increased expression of HMOX1 protein] | PMID:16439612 PMID:18311796 PMID:29353218 | Hmox1 | decreases expression | ISO | Hmox1 (Mus musculus) | 6480464 | CTD | Nitroprusside results in decreased expression of HMOX1 protein | PMID:29353218 | Hmox1 | increases expression | ISO | HMOX1 (Homo sapiens) | 6480464 | CTD | Nitroprusside results in increased expression of HMOX1 mRNA; Nitroprusside results in increased expression of HMOX1 protein | PMID:10349844 PMID:10423162 PMID:8764571 | Hmox1 | multiple interactions | ISO | Hmox1 (Mus musculus) | 6480464 | CTD | Nitroprusside inhibits the reaction [sulforaphane results in increased expression of HMOX1 protein] | PMID:29353218 | Hmox1 | multiple interactions | ISO | HMOX1 (Homo sapiens) | 6480464 | CTD | [linsidomine co-treated with Nitroprusside] results in increased expression of HMOX1 mRNA; [Nitroprusside results in increased abundance of nitrosonium ion] which results in increased expression of HMOX1 mRNA; Dactinomycin inhibits the reaction [Nitroprusside results in increased expression of HMOX1 mRNA]; IFNG protein inhibits the reaction [Nitroprusside results in increased expression of HMOX1 mRNA]; Nitroprusside promotes the reaction [S-Nitrosoglutathione results in increased expression of HMOX1 mRNA]; S-Nitrosoglutathione promotes the reaction [Nitroprusside results in increased expression of HMOX1 mRNA] | PMID:10349844 PMID:10423162 PMID:12393473 PMID:8764571 | | ||||||||||||||||||||||
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