GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Hk2 | decreases expression | EXP | | 6480464 | CTD | Dexamethasone results in decreased expression of HK2 mRNA | PMID:14618091 | Hk2 | multiple interactions | ISO | HK2 (Homo sapiens) | 6480464 | CTD | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of HK2 mRNA | PMID:28628672 | Hk2 | multiple interactions | ISO | Hk2 (Mus musculus) | 6480464 | CTD | [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of HK2 mRNA; Dexamethasone inhibits the reaction [Nickel results in increased expression of HK2 mRNA]; EGF protein inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of HK2 mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of HK2 mRNA] | PMID:16054899 PMID:27452194 | |
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