GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nr3c1 | affects expression | EXP | | 6480464 | CTD | bisphenol A affects the expression of NR3C1 mRNA; bisphenol A affects the expression of NR3C1 protein | PMID:24323913 PMID:24857958 PMID:25181051 PMID:32145629 | Nr3c1 | decreases expression | EXP | | 6480464 | CTD | bisphenol A results in decreased expression of NR3C1 mRNA | PMID:25812946 PMID:26060449 PMID:27697584 PMID:34947998 | Nr3c1 | increases expression | EXP | | 6480464 | CTD | bisphenol A results in increased expression of NR3C1 mRNA | PMID:33296240 PMID:36136478 | Nr3c1 | increases methylation | EXP | | 6480464 | CTD | bisphenol A results in increased methylation of NR3C1 gene | PMID:28505145 | Nr3c1 | increases phosphorylation | EXP | | 6480464 | CTD | bisphenol A results in increased phosphorylation of NR3C1 protein | PMID:34165232 | Nr3c1 | multiple interactions | EXP | | 6480464 | CTD | lithospermate B inhibits the reaction [bisphenol A results in increased phosphorylation of NR3C1 protein]; LY 379268 inhibits the reaction [bisphenol A results in decreased expression of NR3C1 mRNA] | PMID:25812946 PMID:34165232 | Nr3c1 | affects binding | ISO | NR3C1 (Homo sapiens) | 6480464 | CTD | bisphenol A binds to NR3C1 protein | PMID:34706627 | Nr3c1 | affects methylation | ISO | Nr3c1 (Mus musculus) | 6480464 | CTD | bisphenol A affects the methylation of NR3C1 promoter | PMID:27334623 | Nr3c1 | decreases activity | ISO | NR3C1 (Homo sapiens) | 6480464 | CTD | bisphenol A results in decreased activity of NR3C1 protein | PMID:26196221 | Nr3c1 | decreases expression | ISO | Nr3c1 (Mus musculus) | 6480464 | CTD | bisphenol A results in decreased expression of NR3C1 mRNA | PMID:20739668 | Nr3c1 | decreases expression | ISO | NR3C1 (Homo sapiens) | 6480464 | CTD | bisphenol A results in decreased expression of NR3C1 mRNA | PMID:32030086 | Nr3c1 | increases activity | ISO | Nr3c1 (Mus musculus) | 6480464 | CTD | bisphenol A results in increased activity of NR3C1 protein | PMID:19927138 | Nr3c1 | multiple interactions | ISO | Nr3c1 (Mus musculus) | 6480464 | CTD | [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] affects the expression of NR3C1 mRNA; bisphenol A promotes the reaction [[NR3C1 protein co-treated with CEBPB protein] results in increased expression of FABP4 mRNA]; bisphenol A promotes the reaction [[NR3C1 protein co-treated with CEBPD protein] results in increased expression of FABP4 mRNA]; bisphenol A promotes the reaction [NR3C1 protein results in increased expression of FABP4 mRNA]; bisphenol A results in increased activity of and results in increased phosphorylation of NR3C1 protein; MIR21A mRNA affects the reaction [bisphenol A results in increased activity of and results in increased phosphorylation of NR3C1 protein] | PMID:25068083 PMID:26996129 PMID:32518293 | Nr3c1 | multiple interactions | ISO | NR3C1 (Homo sapiens) | 6480464 | CTD | bisphenol A analog inhibits the reaction [Dexamethasone binds to NR3C1 protein]; bisphenol A analog inhibits the reaction [Hydrocortisone results in increased activity of NR3C1 protein]; bisphenol A inhibits the reaction [Dexamethasone binds to NR3C1 protein]; bisphenol A inhibits the reaction [Dexamethasone results in increased activity of NR3C1 protein]; bisphenol A inhibits the reaction [Hydrocortisone binds to NR3C1 protein]; bisphenol A inhibits the reaction [Hydrocortisone results in increased activity of NR3C1 protein]; NR3C1 protein promotes the reaction [bisphenol A results in decreased expression of SCNN1G protein] | PMID:25576683 PMID:26196221 PMID:27522653 PMID:28078411 PMID:30408883 PMID:30582956 PMID:31195007 | |
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