GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ghr | affects response to substance | EXP | | 6480464 | CTD | GHR protein affects the susceptibility to Acetaminophen | PMID:17088403 | Ghr | increases expression | EXP | | 6480464 | CTD | Acetaminophen results in increased expression of GHR mRNA; Acetaminophen results in increased expression of GHR protein | PMID:17088403 PMID:33387578 | Ghr | multiple interactions | EXP | | 6480464 | CTD | N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [Acetaminophen results in increased expression of GHR mRNA] | PMID:17088403 | Ghr | affects expression | ISO | Ghr (Mus musculus) | 6480464 | CTD | Acetaminophen affects the expression of GHR mRNA | PMID:17562736 | Ghr | decreases expression | ISO | GHR (Homo sapiens) | 6480464 | CTD | Acetaminophen results in decreased expression of GHR mRNA | PMID:21420995 PMID:29067470 | Ghr | increases response to substance | ISO | Ghr (Mus musculus) | 6480464 | CTD | GHR gene mutant form results in increased susceptibility to Acetaminophen | PMID:16713617 | |
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