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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2687
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ghr
Name: growth hormone receptor
Acc ID: CHEBI:27363
Term: zinc atom
Definition: A zinc group element atom that has formula Zn.
Chemical ID: MESH:D015032
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ghrdecreases expressionEXP 6480464CTDZinc deficiency results in decreased expression of GHR mRNA; Zinc deficiency results in decreased expression of GHR proteinPMID:10985758 PMID:7722689
Ghrmultiple interactionsEXP 6480464CTDGH1 protein inhibits the reaction [Zinc deficiency results in decreased expression of GHR mRNA]; GH1 protein inhibits the reaction [Zinc deficiency results in decreased expression of GHR protein]PMID:10985758
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