GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Gfap | decreases expression | EXP | | 6480464 | CTD | lead acetate results in decreased expression of GFAP protein | PMID:20829427 | Gfap | increases expression | EXP | | 6480464 | CTD | lead acetate results in increased expression of GFAP mRNA; lead acetate results in increased expression of GFAP protein | PMID:17047031 PMID:33862172 PMID:36539177 | Gfap | multiple interactions | EXP | | 6480464 | CTD | [[sodium arsenite co-treated with lead acetate co-treated with Cadmium Chloride] results in increased phosphorylation of and results in increased activity of PPARG protein] which results in decreased expression of GFAP protein; [Cadmium Chloride co-treated with sodium arsenite co-treated with lead acetate] results in decreased expression of GFAP protein; [lead acetate co-treated with Morphine] results in increased expression of GFAP mRNA; [sodium arsenite co-treated with Cadmium Chloride co-treated with lead acetate] results in increased expression of GFAP protein; [sodium arsenite co-treated with lead acetate co-treated with Cadmium Chloride] promotes the reaction [PPARG protein binds to GFAP promoter]; [sodium arsenite co-treated with lead acetate co-treated with Cadmium Chloride] results in decreased expression of GFAP mRNA; [sodium arsenite co-treated with lead acetate co-treated with Cadmium Chloride] results in decreased expression of GFAP protein; CR8 compound inhibits the reaction [[sodium arsenite co-treated with lead acetate co-treated with Cadmium Chloride] results in decreased expression of GFAP protein] | PMID:20829427 PMID:24481447 PMID:26396915 PMID:26478469 | Gfap | increases expression | ISO | Gfap (Mus musculus) | 6480464 | CTD | lead acetate results in increased expression of GFAP mRNA; lead acetate results in increased expression of GFAP protein | PMID:21322097 PMID:36539177 | Gfap | multiple interactions | ISO | Gfap (Mus musculus) | 6480464 | CTD | pyrrolidine dithiocarbamic acid inhibits the reaction [lead acetate results in increased expression of GFAP mRNA] | PMID:36539177 | | ||||||||||||||||||||||
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