GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Gck | affects expression | EXP | | 6480464 | CTD | Tetrachlorodibenzodioxin affects the expression of GCK mRNA | PMID:22298810 | Gck | decreases expression | EXP | | 6480464 | CTD | Tetrachlorodibenzodioxin results in decreased expression of GCK mRNA | PMID:16054898 PMID:23238561 | Gck | increases expression | EXP | | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of GCK mRNA | PMID:21215274 | Gck | multiple interactions | EXP | | 6480464 | CTD | AHR protein alternative form inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of GCK mRNA] | PMID:21215274 | Gck | affects expression | ISO | Gck (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin affects the expression of GCK mRNA | PMID:18343893 PMID:26377647 | Gck | decreases expression | ISO | Gck (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in decreased expression of GCK mRNA | PMID:15800033 PMID:18163543 PMID:18295293 PMID:18796159 PMID:19770486 PMID:22539624 PMID:23238561 PMID:27562557 | Gck | multiple interactions | ISO | Gck (Mus musculus) | 6480464 | CTD | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GCK mRNA; [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of GCK mRNA | PMID:17942748 PMID:25975270 | |
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