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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2645 Species: Rattus norvegicus RGD Object: Gene Symbol: G6pd Name: glucose-6-phosphate dehydrogenase

Acc ID: CHEBI:64317 Term: isoprenaline Definition: A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders. CasRN: 7683-59-2 Chemical ID: MESH:D007545

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	EXP		6480464	CTD	Atenolol inhibits the reaction [Isoproterenol results in increased activity of G6PD protein] Cycloheximide inhibits the reaction [Isoproterenol results in increased activity of G6PD protein] Gallopamil inhibits the reaction [Isoproterenol results in increased activity of G6PD protein] Dactinomycin inhibits the reaction [Isoproterenol results in increased activity of G6PD protein]	PMID:1978808
increases activity	EXP		6480464	CTD	Isoproterenol results in increased activity of G6PD protein	PMID:1978808