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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2645
Species: Rattus norvegicus
RGD Object: Gene
Symbol: G6pd
Name: glucose-6-phosphate dehydrogenase
Acc ID: CHEBI:18357
Term: (R)-noradrenaline
Definition: The R-enantiomer of noradrenaline.
Chemical ID: MESH:D009638
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
G6pdincreases activityEXP 6480464CTDNorepinephrine results in increased activity of G6PD mRNA; Norepinephrine results in increased activity of G6PD proteinPMID:1378361 PMID:7605896
G6pdincreases expressionEXP 6480464CTDNorepinephrine results in increased expression of G6PD mRNAPMID:7605896
G6pdmultiple interactionsEXP 6480464CTDMetoprolol inhibits the reaction [Norepinephrine results in increased activity of G6PD protein]; Prazosin inhibits the reaction [Norepinephrine results in increased activity of G6PD protein]PMID:1378361
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