Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2626
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fos
Name: Fos proto-oncogene, AP-1 transcription factor subunit
Acc ID: CHEBI:16842
Term: formaldehyde
Definition: An aldehyde resulting from the formal oxidation of methanol.
Chemical ID: MESH:D005557
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fosincreases expressionEXP 6480464CTDFormaldehyde results in increased expression of FOS mRNA; Formaldehyde results in increased expression of FOS proteinPMID:17551412 PMID:20727678 PMID:9149109
Fosmultiple interactionsEXP 6480464CTDKetamine inhibits the reaction [Formaldehyde results in increased expression of FOS protein]; Morphine affects the reaction [Formaldehyde results in increased expression of FOS protein]PMID:17551412 PMID:20727678
Fosincreases expressionISOFOS (Homo sapiens)6480464CTDFormaldehyde results in increased expression of FOS mRNAPMID:17938736 PMID:20655997 PMID:28937961
Go Back to source page   Continue to Ontology report