GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Esr2 | affects binding | EXP | | 8694130 | RGD | 5alpha-dihydrotestosterone binds to Esr2 protein | | Esr2 | decreases expression | ISO | ESR2 (Homo sapiens) | 6480464 | CTD | Dihydrotestosterone results in decreased expression of ESR2 mRNA; Dihydrotestosterone results in decreased expression of ESR2 protein | PMID:18007998 | Esr2 | increases activity | ISO | ESR2 (Homo sapiens) | 6480464 | CTD | Dihydrotestosterone results in increased activity of ESR2 protein | PMID:15171712 | Esr2 | increases localization | ISO | ESR2 (Homo sapiens) | 6480464 | CTD | Dihydrotestosterone results in increased localization of ESR2 protein | PMID:15171712 | Esr2 | multiple interactions | ISO | ESR2 (Homo sapiens) | 6480464 | CTD | AR protein mutant form affects the reaction [Dihydrotestosterone results in decreased expression of ESR2 protein]; fulvestrant inhibits the reaction [Dihydrotestosterone results in increased activity of ESR2 protein]; fulvestrant inhibits the reaction [Dihydrotestosterone results in increased localization of ESR2 protein] | PMID:15171712 PMID:18007998 | |
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