A phthalate ester that is the bis(2-ethylhexyl) ester of benzene-1,2-dicarboxylic acid.
Chemical ID:
MESH:D004051
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Diethylnitrosamine] results in increased expression of ESR1 mRNA; [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Diethylnitrosamine] results in increased expression of ESR1 protein; [bisphenol A co-treated with Diethylhexyl Phthalate] promotes the reaction [[Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 mRNA]; [bisphenol A co-treated with Diethylhexyl Phthalate] promotes the reaction [[Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 protein]; [bisphenol A co-treated with Diethylhexyl Phthalate] results in increased expression of ESR1 mRNA; [bisphenol A co-treated with Diethylhexyl Phthalate] results in increased expression of ESR1 protein; [Diethylhexyl Phthalate co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 mRNA; [Diethylhexyl Phthalate co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 protein; [Diethylhexyl Phthalate co-treated with Diethylnitrosamine] results in increased expression of ESR1 mRNA; [Diethylhexyl Phthalate co-treated with Diethylnitrosamine] results in increased expression of ESR1 protein; [Diethylhexyl Phthalate co-treated with Genistein] results in decreased expression of ESR1 mRNA
[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of ESR1 protein; [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of ESR1 protein; [Dietary Sucrose co-treated with Dietary Fats co-treated with bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] affects the expression of ESR1 mRNA; [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of ESR1 mRNA; [Diethylhexyl Phthalate co-treated with Chlorodiphenyl (54% Chlorine)] results in decreased expression of ESR1 mRNA; [Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in increased expression of ESR1 mRNA; [Tetrachlorodibenzodioxin co-treated with bisphenol A co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with Dietary Fats] results in increased expression of ESR1 mRNA; [Tetrachlorodibenzodioxin co-treated with bisphenol A co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate] inhibits the reaction [Dietary Fats results in increased expression of ESR1 mRNA]; [Tetrachlorodibenzodioxin co-treated with bisphenol A co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate] inhibits the reaction [Dietary Fats results in increased expression of ESR1 protein]; PPARA gene mutant form inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of ESR1]
[Diethylhexyl Phthalate results in increased abundance of 2-ethyl-5-carboxypentyl phthalate] which results in decreased expression of ESR1 protein; [Diethylhexyl Phthalate results in increased abundance of mono(2-ethyl-5-oxohexyl)phthalate] which results in increased expression of ESR1 protein; [Oxygen deficiency co-treated with Diethylhexyl Phthalate] results in decreased expression of ESR1 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diethylhexyl Phthalate inhibits the reaction [AHR protein results in increased expression of ESR1 protein]]; Diethylhexyl Phthalate binds to and results in decreased activity of ESR1 protein; Diethylhexyl Phthalate binds to and results in increased activity of ESR1 protein; Diethylhexyl Phthalate inhibits the reaction [AHR protein results in increased expression of ESR1 protein]; Diethylhexyl Phthalate inhibits the reaction [Estradiol binds to ESR1 protein]; Diethylhexyl Phthalate inhibits the reaction [Estradiol results in increased activity of ESR1 protein]; Diethylhexyl Phthalate inhibits the reaction [Vincristine results in decreased expression of ESR1 mRNA]; Diethylhexyl Phthalate inhibits the reaction [Vincristine results in decreased expression of ESR1 protein]; ESR1 promotes the reaction [Diethylhexyl Phthalate inhibits the reaction [Camptothecin results in increased expression of ATM protein modified form]]; ESR1 promotes the reaction [Diethylhexyl Phthalate inhibits the reaction [Camptothecin results in increased expression of H2AX protein modified form]]; Oxygen deficiency promotes the reaction [Diethylhexyl Phthalate results in decreased expression of ESR1 mRNA]; Tamoxifen inhibits the reaction [Diethylhexyl Phthalate binds to and results in increased activity of ESR1 protein]
