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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2553
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Eno1
Name: enolase 1
Acc ID: CHEBI:2682
Term: amphotericin B
Definition: A macrolide antibiotic used to treat potentially life-threatening fungal infections.
Chemical ID: MESH:D000666
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Eno1multiple interactionsISOENO1 (Homo sapiens)6480464CTDAmphotericin B inhibits the reaction [Oxygen deficiency results in increased expression of ENO1 mRNA]; Amphotericin B results in increased expression of and results in increased secretion of ENO1 proteinPMID:16189267 PMID:26259607
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