GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Egfr | increases activity | EXP | | 6480464 | CTD | Deoxycholic Acid results in increased activity of EGFR protein | PMID:14747693 | Egfr | decreases response to substance | ISO | EGFR (Homo sapiens) | 6480464 | CTD | EGFR protein results in decreased susceptibility to Deoxycholic Acid | PMID:12507930 | Egfr | increases activity | ISO | EGFR (Homo sapiens) | 6480464 | CTD | Deoxycholic Acid results in increased activity of EGFR protein | PMID:16213893 | Egfr | increases phosphorylation | ISO | EGFR (Homo sapiens) | 6480464 | CTD | Deoxycholic Acid results in increased phosphorylation of EGFR protein | PMID:14747693 | Egfr | multiple interactions | ISO | EGFR (Homo sapiens) | 6480464 | CTD | Deoxycholic Acid results in decreased glycosylation of and results in decreased expression of EGFR protein; Erlotinib Hydrochloride promotes the reaction [Deoxycholic Acid results in decreased glycosylation of and results in decreased expression of EGFR protein]; Ursodeoxycholic Acid inhibits the reaction [Deoxycholic Acid results in increased phosphorylation of EGFR protein] | PMID:14747693 PMID:22223758 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |