GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Egfr | increases phosphorylation | EXP | | 6480464 | CTD | Hydrogen Peroxide results in increased phosphorylation of EGFR protein | PMID:19885844 | Egfr | affects expression | ISO | EGFR (Homo sapiens) | 6480464 | CTD | Hydrogen Peroxide affects the expression of EGFR protein | PMID:21179406 | Egfr | increases phosphorylation | ISO | Egfr (Mus musculus) | 6480464 | CTD | Hydrogen Peroxide results in increased phosphorylation of EGFR protein | PMID:14737115 | Egfr | multiple interactions | ISO | Egfr (Mus musculus) | 6480464 | CTD | AG 1879 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of EGFR protein] | PMID:14737115 | Egfr | multiple interactions | ISO | EGFR (Homo sapiens) | 6480464 | CTD | Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of and results in increased activity of EGFR protein]; EGFR mutant form inhibits the reaction [Hydrogen Peroxide results in increased expression of MMP9 mRNA]; Hydrogen Peroxide inhibits the reaction [tubeimoside II inhibits the reaction [TGFB1 protein results in increased phosphorylation of and results in increased oxidation of EGFR protein]]; Hydrogen Peroxide results in increased phosphorylation of and results in increased activity of EGFR protein | PMID:10640773 PMID:26514923 PMID:33412154 | | ||||||||||||||||||||||
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