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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2542 Species: Rattus norvegicus RGD Object: Gene Symbol: Egf Name: epidermal growth factor

Acc ID: CHEBI:27385 Term: tetrachloromethane Definition: A chloromethane that has formula CCl4. CasRN: 56-23-5 Chemical ID: MESH:D002251

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	EXP		6480464	CTD	Carbon Tetrachloride results in increased expression of EGF mRNA	PMID:17631135 PMID:16097045
multiple interactions	EXP		6480464	CTD	IL10 protein affects the reaction [Carbon Tetrachloride results in increased expression of EGF mRNA] IL10 protein affects the reaction [Carbon Tetrachloride results in increased expression of EGF protein]	PMID:16097045
increases expression	EXP		6480464	CTD	Carbon Tetrachloride results in increased expression of EGF mRNA	PMID:16097045 PMID:17631135