GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Edn1 | decreases expression | EXP | | 6480464 | CTD | cobaltous chloride results in decreased expression of EDN1 mRNA | PMID:15948191 | Edn1 | increases expression | EXP | | 6480464 | CTD | cobaltous chloride results in increased expression of EDN1 mRNA; cobaltous chloride results in increased expression of EDN1 protein | PMID:11078357 PMID:11078377 PMID:25469848 | Edn1 | decreases expression | ISO | EDN1 (Homo sapiens) | 6480464 | CTD | cobaltous chloride results in decreased expression of EDN1 mRNA | PMID:19320972 | Edn1 | increases expression | ISO | EDN1 (Homo sapiens) | 6480464 | CTD | cobaltous chloride results in increased expression of EDN1 mRNA; cobaltous chloride results in increased expression of EDN1 protein | PMID:10939628 PMID:25469848 PMID:27297870 PMID:29165873 | Edn1 | increases secretion | ISO | EDN1 (Homo sapiens) | 6480464 | CTD | cobaltous chloride results in increased secretion of EDN1 protein | PMID:27297870 | Edn1 | multiple interactions | ISO | EDN1 (Homo sapiens) | 6480464 | CTD | 8-bromocyclic GMP inhibits the reaction [cobaltous chloride results in increased expression of EDN1 mRNA]; 8-bromocyclic GMP inhibits the reaction [cobaltous chloride results in increased expression of EDN1 protein]; andrographolide inhibits the reaction [cobaltous chloride results in increased expression of EDN1 mRNA]; andrographolide inhibits the reaction [cobaltous chloride results in increased expression of EDN1 protein]; Bilirubin inhibits the reaction [cobaltous chloride results in increased expression of EDN1 mRNA]; Bilirubin inhibits the reaction [cobaltous chloride results in increased secretion of EDN1 protein]; cobaltous chloride promotes the reaction [HIF1A protein binds to ARNT protein binds to EDN1 promoter]; Genistein affects the reaction [cobaltous chloride promotes the reaction [HIF1A protein binds to ARNT protein binds to EDN1 promoter]]; Genistein inhibits the reaction [cobaltous chloride results in increased expression of EDN1 mRNA]; SB 203580 inhibits the reaction [cobaltous chloride results in increased secretion of EDN1 protein]; tricarbonyldichlororuthenium (II) dimer inhibits the reaction [cobaltous chloride results in increased expression of EDN1 mRNA]; tricarbonyldichlororuthenium (II) dimer inhibits the reaction [cobaltous chloride results in increased expression of EDN1 protein]; tricarbonyldichlororuthenium (II) dimer inhibits the reaction [cobaltous chloride results in increased secretion of EDN1 protein]; Vanadates inhibits the reaction [andrographolide inhibits the reaction [cobaltous chloride results in increased expression of EDN1 mRNA]]; Vanadates inhibits the reaction [andrographolide inhibits the reaction [cobaltous chloride results in increased expression of EDN1 protein]] | PMID:10939628 PMID:27297870 PMID:29165873 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |