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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2532
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Edn1
Name: endothelin 1
Acc ID: CHEBI:15756
Term: hexadecanoic acid
Definition: A straight-chain, sixteen-carbon, saturated long-chain fatty acid.
Chemical ID: MESH:D019308
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Edn1decreases expressionISOEDN1 (Homo sapiens)6480464CTDPalmitic Acid results in decreased expression of EDN1 proteinPMID:35747990
Edn1increases expressionISOEDN1 (Homo sapiens)6480464CTDPalmitic Acid results in increased expression of EDN1 mRNA; Palmitic Acid results in increased expression of EDN1 proteinPMID:16895544
Edn1multiple interactionsISOEDN1 (Homo sapiens)6480464CTDAgmatine inhibits the reaction [Palmitic Acid results in decreased expression of EDN1 protein]PMID:35747990
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