GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Drd1 | affects binding | EXP | | 6480464 | CTD | Clozapine binds to DRD1 protein | PMID:9723970 | Drd1 | affects binding | ISO | Drd1 (Mus musculus) | 6480464 | CTD | Clozapine analog binds to DRD1 protein | PMID:11997696 | Drd1 | affects binding | ISO | DRD1 (Homo sapiens) | 6480464 | CTD | Clozapine binds to DRD1 protein | PMID:11997696 PMID:1352677 | Drd1 | affects response to substance | ISO | DRD1 (Homo sapiens) | 6480464 | CTD | DRD1 gene polymorphism affects the susceptibility to Clozapine; DRD1 protein affects the susceptibility to Clozapine | PMID:17092969 | Drd1 | decreases expression | ISO | Drd1 (Mus musculus) | 6480464 | CTD | Clozapine results in decreased expression of DRD1 mRNA | PMID:17266109 | |
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