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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2518
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Drd1
Name: dopamine receptor D1
Acc ID: CHEBI:27750
Term: ethyl acetate
Definition: The acetate ester formed between acetic acid and ethanol.
Chemical ID: MESH:C007650
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Drd1multiple interactionsEXP 6480464CTD[2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine binds to and results in increased activity of DRD1 protein] which results in increased susceptibility to ethyl acetate; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [[2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine binds to and results in increased activity of DRD1 protein] which results in increased susceptibility to ethyl acetate]PMID:9537685
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