GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Dpp4 | decreases expression | ISO | DPP4 (Homo sapiens) | 6480464 | CTD | Doxorubicin results in decreased expression of DPP4 mRNA | PMID:29803840 | Dpp4 | increases response to substance | ISO | DPP4 (Homo sapiens) | 6480464 | CTD | DPP4 protein results in increased susceptibility to Doxorubicin | PMID:15753397 | Dpp4 | multiple interactions | ISO | DPP4 (Homo sapiens) | 6480464 | CTD | [DPP4 protein results in increased expression of TOP2A protein] which results in increased susceptibility to Doxorubicin; DPP4 protein promotes the reaction [Doxorubicin results in increased cleavage of PARP1 protein] | PMID:15753397 | | ||||||||||||||||||||||
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