GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp2e1 | increases metabolic processing | EXP | | 6480464 | CTD | CYP2E1 protein results in increased metabolism of Phenol | PMID:8211999 | Cyp2e1 | multiple interactions | EXP | | 6480464 | CTD | [CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of Phenol; [CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of catechol; [CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of hydroquinone; [Glutathione co-treated with [CYP2E1 protein results in increased metabolism of Phenol]] results in increased chemical synthesis of [Glutathione binds to hydroquinone metabolite]; EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of Phenol]; EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of catechol]; EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of hydroquinone]; EPHX1 protein promotes the reaction [CYP2E1 protein results in increased metabolism of Phenol] | PMID:8211999 | Cyp2e1 | increases metabolic processing | ISO | Cyp2e1 (Mus musculus) | 6480464 | CTD | CYP2E1 protein results in increased metabolism of Phenol | PMID:11701230 | Cyp2e1 | multiple interactions | ISO | CYP2E1 (Homo sapiens) | 6480464 | CTD | [CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of Phenol | PMID:15051535 | | ||||||||||||||||||||||
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