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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2460
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp1b1
Name: cytochrome P450, family 1, subfamily b, polypeptide 1
Acc ID: CHEBI:22984
Term: calcium atom
Definition: An alkaline earth metal atom that has formula Ca.
Chemical ID: MESH:D002118
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp1b1multiple interactionsISOCyp1b1 (Mus musculus)6480464CTDCalcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]PMID:19782052
Cyp1b1multiple interactionsISOCYP1B1 (Homo sapiens)6480464CTDCalcium promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; Calcium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]PMID:16237193
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